Advances in microscopy has helped study complex questions of locomotion: Prof VijayRaghavan

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Professor K. VijayRaghavan, Principal Scientific Adviser to the Government of India, has highlighted how advances in microscopy has helped in the study of complex questions of walking and flying by allowing us to witness the cells at their finest resolution and revealing the specific components of the cells as well as their functions. He was … Read more

Synthetic organelle shows how tiny puddle-organs in our cells work

A couple of sugars, a dash of enzymes, a pinch of salt, a splash of polyethylene glycol, carefully arranged in watery baths. And researchers had made a synthetic organelle, which they used in a new study to explore some odd cellular biochemistry. The researchers at the Georgia Institute of Technology made the chemical medley in … Read more

How damaging immune cells develop during tuberculosis

Insights into how harmful white blood cells form during tuberculosis infection point to novel targets for pharmacological interventions, according to a study published in the open-access journal PLOS Pathogens by Valentina Guerrini and Maria Laura Gennaro of Rutgers New Jersey Medical School, and colleagues. Foam cells are a type of white blood cell, known as … Read more

DNA accessibility, gene expression jointly profiled in thousands of cells

Scientists have now developed an assay that concurrently profiles both the epigenome and transcriptome of each of thousands of single cells. The epigenome and transcriptome are part of the molecular biology that converts a genetic blueprint into tools and materials for living cells. The genomes of different types of cells may be identical, while their … Read more

Autism linked to egg cells’ difficulty creating large proteins

New work from Carnegie’s Ethan Greenblatt and Allan Spradling reveals that the genetic factors underlying fragile X syndrome, and potentially other autism-related disorders, stem from defects in the cell’s ability to create unusually large protein structures. Their findings are published in Science. Their work focuses on a gene called Fmr1. Mutations in this gene create … Read more

This matrix delivers healing stem cells to injured elderly muscles

A car accident leaves an aging patient with severe muscle injuries that won’t heal. Treatment with muscle stem cells from a donor might restore damaged tissue, but doctors are unable to deliver them effectively. A new method may help change this. Researchers at the Georgia Institute of Technology engineered a molecular matrix, a hydrogel, to … Read more

E-cigarette vapor disables key immune cells in the lung and boosts inflammation

E-cigarette vapour boosts the production of inflammatory chemicals and disables key protective cells in the lung that keep the air spaces clear of potentially harmful particles, reveals a small experimental study, published online in the journal Thorax. The vapour impairs the activity of alveolar macrophages, which engulf and remove dust particles, bacteria, and allergens that … Read more

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