Tuesday , September 21 2021

NeuroGen Brain & Spine Institute Stem Cell Therapy A New Hope Of Treatment For Children Affected With Global Development Delay

Udaipur: NeuroGen Brain and Spine Institute, based out of Mumbai and is India’s leading Stem Cell Therapy Centre that offers a comprehensive approach for children with Neurological Disorders.

Neurogen BSI has been set up to help patients suffering from incurable neurological disorders, get relief from their symptoms and physical disabilities by the use of stem cell therapy in a safe and effective way. NeuroGen BSI offers stem cell therapy and holistic rehabilitation for Neurological Disorders like Autism, cerebral palsy, mental retardation, brain stroke, muscular dystrophy, spinal cord injury, head injury, Cerebellar ataxia, dementia, motor neuron disease, multiple sclerosis and neuropsychiatric disorders.  Till date, the organization has already successfully treated 6000 patients from over 50 countries.

NeuroGen Brain and Spine Institute is organizing a free workshop cum OPD consultation camp on May 13, 2018 in Udaipur city for all Neurological disorders patients residing in Rajasthan. This camp is being organized to facilitate the patients as NeuroGen understands patients with spinal cord injury, muscular dystrophy, Autism, Cerebral Palsy, etc traveling is extremely difficult all the way to Mumbai for just consultation purpose. All those patients suffering from such incurable neurological disorders can contact for appointments for this free camp to Mona 09920200400 / Pushkala 09821529653.

Dr Alok Sharma Professor & Head of Neurosurgery, LTMG Hospital & LTM Medical College, Sion Mumbai and Director NeuroGen Brain & Spine Institute said “A look at the development of the advances in the medical sciences shows that the solutions to difficult untreatable disorders have always come from a multi-disciplinary approach. It is only when people from different specialties pool their knowledge, skills and resources, that breakthroughs happen in incurable or difficult to treat medical conditions.”

Global Delay Development (GDD) is an abnormality of motor function, mental function and postural tone that is acquired at an early age, even before birth. This abnormality in the motor system is the result of brain lesions that are non progressive. The motor system of the body provides the ability to move and control movements. The abnormality in these systems means that it affects the Childs ability to perform activities of daily activities and affects their ability to move and walk.

Dr Nandini Gokulchandran, Deputy Director and Head Medical Services, NeuroGen Brain and Spine Institute said “Signs and symptoms of Global developmental delay usually show in the first year of life. The predominant symptoms and signs of GDD are related to motor difficulties, which are the consequence of the brain damage. The extension and severity of the brain lesion is the leading factor in the magnitude of the motor deficit. Many of the symptoms observed in these children are related to the primary problem that is impaired motor functions. Some of the symptoms a child may display would include developmental motor delay, gait disorders, poor fine and gross motor coordination, swallowing disorders, or speech delay are all the result of the basic motor disorder. GDD affects approximately one to three out of every thousand children born. However, it is much higher in infants born with very low weight and in premature infants. Most of the causes of GDD do not have specific, curative treatments.”

Dr Nandini Gokulchandran further said “However, children with GDD present many medical problems that can be treated or prevented. The initial stage of treatment involves an interdisciplinary team, consisting of a pediatrician, preferable one with experience in neurodevelopment disorders, a neurologist (or other neurological practitioner), a mental health practitioner, an orthopedic surgeon, a physical therapist, a speech therapist, and an occupational therapist. Each member of the team has important, independent contributions to make in the care of the affected child.”

Dr Nandini Gokulchandran said “Although, these treatment option help improve the quality of life for these patients, they do not solve the problem to its core. Modern medicine and research have together thrown light on the potential use of stem cells for curbing the disastrous effects seen in GDD.”

Today we are presenting a case report of Hiba Khan, who is a 5 years old female and a known case of Global Developmental Disorder with Microcephaly, with no family history of it or other psychological disorders.

Hiba was born a full-term delivery by cesarean, due to mucus congestion in lungs. She did not cry immediately after birth. All her motor milestones were delayed. She was taken to Children’s specialist at around 1 year of age and due to frequent illness where she was recommended to undergo a MRI. This suggested some deformity in brain leading to developmental delay. Hiba’s parents consulted two to three doctors but no one suggested any treatment for the same. At the age of 1.5 years, Hiba started suffering a series of seizures. The first one lasting for about 5 mins was a silent seizure during which she was fisting with froth coming out of her mouth followed by bluish coloration of lips. She was unconscious for 8 hrs post this episode. Physiotherapy was started along with some anti-epileptic drugs. Such occurrences kept on happening with a total of 4 more episodes with almost the same outcome and condition.

When Hiba’s parents learnt about that their child can be treated through stem cell therapy they immediately consulted the doctors from NeuroGen, sent reports to the doctors through telephone and e mail, and when they received a positive response from NeuroGen experts that Stem Cell Therapy followed by Neuro Rehabilitation can help their child, Hiba visited NeuroGen in November 2017 for treatment.

On examination the Chief complaints found in Hiba was that of Poor attention, could not arouse and sustain. Could not follow instructions. Poor cognitive abilities, not age appropriate (could not perform as per her current age on reasoning, abstract thinking, memory, comprehension). Poor (No) Judgment in respect to danger and surround. No awareness. Could not imitate actions and gestures. Could not receive and expressed emotions appropriately. Poor in social interaction, could not pursue basic level relationship.Could not speak.Poor communicative skills.Could not understand Verbal & Nonverbal cues.Could not convey her needs.She was dependent for All Day Living Activities such as eating, dressing, etc. She was not toilet trained.

At NeuroGen Brain and Spine Institute, Hiba underwent Stem Cell Therapy along with a customized rehabilitation program. The aim of the rehabilitation program was to develop cognition and understanding, therapies to reduce the hyperactivity and to increase the concentration, command following and to increase overall intellectual ability of the patient. She was given exercises that would help her improve understanding, address her behavior, sensory and motor issues. She was given a combination program with occupational therapy, physiotherapy, speech therapy and psychological counseling under the guidance of the most experienced professionals in the field. This helped her to help develop her overall skills, abilities and overall development. These exercises carried out in a systematic pattern with sufficient rest intervals to the patient. Together, the aim of the rehabilitation program was to improve her overall quality of life. Occupational therapy and rehabilitation taught at NeuroGen were continued after going home.

The improvements seen in Hiba after Stem Cell therapy are that now Hiba can now recognize objects and family members.Orientation to place has improved.Reduction in stubborn behavior.Memory has improved.Improvement in posture and overall strength in upper and lower limbs.Improved gait. Lying, sitting and standing tolerance has improved.Chewing, swallowing, eye contact, danger awareness has improved.Improvements in All Day Living Activities.Indicates bladder and bowel movements through gestures. Responsiveness towards commands has improved.

“Hiba is showing gradual and noticeable improvement”, says Mrs. Shakila Khan, Maternal Grand Mother of Hiba. “Kids who face such difficulties at an early age should be shown acceptance and loved equally. This gives them a better scope of recovery”, Mrs. Shakila adds

Concluded Dr Alok Sharma saying, “Stem cell therapy is emerging as one of the newer treatment options for autism, cerebral palsy, global developmental delay and other neurological disorders. This treatment has the potential to repair the damaged neural tissue at molecular, structural and functional level. “

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