Several people are feared trapped under the debris while the rescue operation is underway.
The blast took place around 4 pm at the factory located in a residential area.
Of the 14 seriously injured people, four have been referred to the Amritsar government hospital, Bhalla added.
Teams of the National Disaster Response Force (NDRF) and the State Disaster Response Force (SDRF) have been deployed for the rescue operation.
Senior officials of the district administration and police have reached the spot to take stock of the situation.